LMTK2 antibody (AA 675-725)

Catalog No. ABIN7453121

Product Details anti-LMTK2 Antibody

Target: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Binding Specificity: AA 675-725

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMTK2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-LMTK2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 675 and 725

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for LMTK2

Target: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Alternative Name: LMTK2 (LMTK2 Products)

Synonyms: AATYK2 antibody, BREK antibody, KPI-2 antibody, KPI2 antibody, LMR2 antibody, cprk antibody, 2900041G10Rik antibody, A330101P12Rik antibody, aatyk2 antibody, lemur tyrosine kinase 2 antibody, LMTK2 antibody, Lmtk2 antibody

Background: Background: Lemur tyrosine kinase (LMTK2) belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. LMTK2 interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. LMTK2 is involved in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggest an essential role of this protein in spermatogeness [taken from NCBI Entrez Gene (Gene ID: 22853)].

Gene ID: 22853

NCBI Accession: NP_055731

UniProt: Q8IWU2

Pathways: RTK Signaling, Neurotrophin Signaling Pathway