PSMD12 antibody (AA 1-50)
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- Target See all PSMD12 Antibodies
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
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Binding Specificity
- AA 1-50
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMD12 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit anti-PSMD12 Antibody, Affinity Purified
- Predicted Reactivity
- Mouse,Bovine,Orangutan
- Purification
- Affinity Purified
- Immunogen
- Between AA 1 and 50
- Isotype
- IgG
- Top Product
- Discover our top product PSMD12 Primary Antibody
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- Application Notes
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IP: Not recommended
WB: 1:1,000 - 1:5,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
- Alternative Name
- PSMD12 (PSMD12 Products)
- Synonyms
- wu:fb38a06 antibody, wu:fc34f08 antibody, wu:fc49f02 antibody, PSMD12 antibody, rpn5 antibody, Rpn5 antibody, p55 antibody, 1500002F15Rik antibody, AI480719 antibody, P55 antibody, proteasome 26S subunit, non-ATPase 12 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 antibody, psmd12 antibody, PSMD12 antibody, Psmd12 antibody
- Background
- Background: Proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (PSMD12) is a subunit of the 26S proteasome, a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD12 is a non-ATPase subunit of the 19S regulator. [taken from NCBI Entrez Gene (Gene ID: 5718)].
- Gene ID
- 5718
- NCBI Accession
- NP_002807
- UniProt
- O00232
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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