CDC42EP1 antibody (AA 300-350)

Catalog No. ABIN7452698

Product Details anti-CDC42EP1 Antibody

Target: CDC42EP1 (CDC42 Effector Protein (Rho GTPase Binding) 1 (CDC42EP1))

Binding Specificity: AA 300-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42EP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-BORG5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IP: 5 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CDC42EP1

Target: CDC42EP1 (CDC42 Effector Protein (Rho GTPase Binding) 1 (CDC42EP1))

Alternative Name: BORG5 (CDC42EP1 Products)

Synonyms: BORG5 antibody, CEP1 antibody, MSE55 antibody, 1810058K22Rik antibody, AA980734 antibody, Borg5 antibody, CDC42 effector protein 1 antibody, CDC42 effector protein (Rho GTPase binding) 1 antibody, CDC42EP1 antibody, Cdc42ep1 antibody

Background: Background: BORG5 (binder of Rho GTPases 5) is part of a family of proteins that function as negative regulators of CDC42 Rho GTPase signaling. The Borg family of proteins are also known as CEPs (Cdc effector proteins) and have been shown to act downstream of Cdc42 to influence the assembly of actin filaments and changes in cell shape. BORG5 plays a role in mannose receptor-mediated phagocytosis of unopsonized Pneumocystis organisms by alveolar macrophages.

Gene ID: 11135

NCBI Accession: NP_689449

UniProt: Q00587