CDK5RAP2 antibody (AA 900-950)

Catalog No. ABIN7452677

Product Details anti-CDK5RAP2 Antibody

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Binding Specificity: AA 900-950

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5RAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-CDK5RAP2 Antibody, Affinity Purified

Predicted Reactivity: Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 900 and 950

Isotype: IgG

Application Details

Application Notes:

IP: 3 - 5 μg/mg lysate

WB: 1:2,500 - 1:15,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CDK5RAP2

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Alternative Name: CDK5RAP2 (CDK5RAP2 Products)

Synonyms: EGFL5 antibody, C48 antibody, Cep215 antibody, MCPH3 antibody, 2900018K03Rik antibody, an antibody, mKIAA1633 antibody, CDK5 regulatory subunit associated protein 2 antibody, CDK5 regulatory subunit-associated protein 2 antibody, CDK5RAP2 antibody, LOC100156240 antibody, cdk5rap2 antibody, Cdk5rap2 antibody

Background: Background: Mutations in CDK5RAP2 (CDK5 regulatory subunit-associated protein 2) have been linked to microcephaly. CDK5RAP2 may be involved in centrosome directed production of microtubules and mitotic spindle formation during neural cell division. CDK5RAP2 associates with the activating subunit of Cdk5, p25NCK5A. Cdk5 is a brain specific cyclin-dependent kinase important to mammalian brain development.

Gene ID: 55755

NCBI Accession: NP_060719

UniProt: Q96SN8

Pathways: M Phase, SARS-CoV-2 Protein Interactome