KIDINS220 antibody (AA 1721-1771)
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- Target See all KIDINS220 Antibodies
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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Binding Specificity
- AA 1721-1771
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KIDINS220 antibody is un-conjugated
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Application
- Immunoprecipitation (IP)
- Purpose
- Rabbit anti-ARMS Antibody, Affinity Purified
- Predicted Reactivity
- Rat
- Purification
- Affinity Purified
- Immunogen
- between AA 1721 and 1771
- Isotype
- IgG
- Top Product
- Discover our top product KIDINS220 Primary Antibody
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- Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
- Alternative Name
- ARMS (KIDINS220 Products)
- Synonyms
- ARMS antibody, fj35h03 antibody, kidins220 antibody, zgc:63531 antibody, dZ119J18.2 antibody, wu:fj35h03 antibody, 3110039L19Rik antibody, AI194387 antibody, AI316525 antibody, C330002I19Rik antibody, mKIAA1250 antibody, kinase D interacting substrate 220 antibody, kinase D-interacting substrate 220 antibody, kinase D-interacting substrate 220b antibody, kinase D-interacting substrate 220kDa antibody, KIDINS220 antibody, Kidins220 antibody, kidins220b antibody
- Background
- Background: Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) Q9ULH0].
- Gene ID
- 57498
- NCBI Accession
- NP_065789
- UniProt
- Q9ULH0
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