EVI5 antibody (AA 525-575)

Catalog No. ABIN7452324

Product Details anti-EVI5 Antibody

Target: EVI5 (Ecotropic Viral Integration Site 5 (EVI5))

Binding Specificity: AA 525-575

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EVI5 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-EVI5 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 525 and 575

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-EVI5 antibody ABIN7451777.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EVI5

Target: EVI5 (Ecotropic Viral Integration Site 5 (EVI5))

Alternative Name: EVI5 (EVI5 Products)

Synonyms: NB4S antibody, evi5 antibody, im:7145726 antibody, zgc:123024 antibody, ecotropic viral integration site 5 antibody, ecotropic viral integration site 5b antibody, EVI5 antibody, Evi5 antibody, evi5b antibody

Background: Background: The EVI5 oncogene has been identified as a protein that is localized to the centrosome and mitotic spindle, and in association with the aurora B complex, facilitates cytokinesis. EVI5 also appears to prevent premature APC/C activation and mitotic progression by stabilizing the anaphase-promoting complex/cyclosome (APC/C) inhibitor, Emi1, as well as cyclin A. EVI5 has also been demonstrated to be a binding partner of the Rab11 GTPase that regulates intracellular transport and cytokinesis.

Gene ID: 7813

NCBI Accession: NP_005656

UniProt: O60447