ERCC5 antibody (AA 1136-1186)
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- Target See all ERCC5 Antibodies
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
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Binding Specificity
- AA 1136-1186
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ERCC5 antibody is un-conjugated
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Application
- Immunoprecipitation (IP)
- Purpose
- Rabbit anti-ERCC5/XPG Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- between AA 1136 and 1186
- Isotype
- IgG
- Top Product
- Discover our top product ERCC5 Primary Antibody
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- Application Notes
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-ERCC5/XPG antibody ABIN7453883.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
- Alternative Name
- ERCC5/XPG (ERCC5 Products)
- Synonyms
- COFS3 antibody, ERCM2 antibody, UVDR antibody, XPG antibody, XPGC antibody, cofs3 antibody, ercm2 antibody, uvdr antibody, xpg antibody, xpgc antibody, Xpg antibody, ERCC excision repair 5, endonuclease antibody, excision repair cross-complementation group 5 L homeolog antibody, excision repair cross-complementing rodent repair deficiency, complementation group 5 antibody, ERCC5 antibody, ercc5.L antibody, Ercc5 antibody
- Background
- Background: ERCC5 is a single-stranded DNA endonuclease involved in DNA excision repair. ERCC5 is an important component of the nucleotide excision repair (NER) pathway which is critical to the repair of DNA lesions caused by exposure to UV light. Defects in ERCC5 are the cause of xeroderma pigmentosum, an autosomal recessive disease characterized by a hypersensitivity to sunlight and a high predisposition to cancer on UV-exposed areas.
- Gene ID
- 2073
- NCBI Accession
- NP_000114
- UniProt
- P28715
- Pathways
- DNA Damage Repair
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