ERCC5 antibody (AA 1136-1186)

Catalog No. ABIN7452322

Product Details anti-ERCC5 Antibody

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Binding Specificity: AA 1136-1186

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC5 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-ERCC5/XPG Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1136 and 1186

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-ERCC5/XPG antibody ABIN7453883.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ERCC5

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Alternative Name: ERCC5/XPG (ERCC5 Products)

Background: Background: ERCC5 is a single-stranded DNA endonuclease involved in DNA excision repair. ERCC5 is an important component of the nucleotide excision repair (NER) pathway which is critical to the repair of DNA lesions caused by exposure to UV light. Defects in ERCC5 are the cause of xeroderma pigmentosum, an autosomal recessive disease characterized by a hypersensitivity to sunlight and a high predisposition to cancer on UV-exposed areas.

Gene ID: 2073

NCBI Accession: NP_000114

UniProt: P28715

Pathways: DNA Damage Repair