DOCK11 antibody (AA 100-150)

Catalog No. ABIN7452227

Product Details anti-DOCK11 Antibody

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Binding Specificity: AA 100-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK11 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-DOCK11 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 100 and 150

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452227 has not performed satisfactorily when used for WB of DOCK11 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of DOCK11.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DOCK11

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Alternative Name: DOCK11 (DOCK11 Products)

Synonyms: ACG antibody, ZIZ2 antibody, bB128O4.1 antibody, 5033414A21Rik antibody, 8030476J24 antibody, Zizimin2 antibody, sph238 antibody, dedicator of cytokinesis 11 antibody, DOCK11 antibody, Dock11 antibody

Background: Background: DOCK11 (dedicator of cytokinesis 11) is also known as zizimin-2. It is a DOCK180-related guanine nucleotide exchange factor (GEF) for the small GTPase, Cdc42. As a GEF, DOCK11 functions to catalyze the dissociation of GDP from the GTPase. Dissociation of GDP allows an exchange for GTP and subsequent downstream signaling by the GTPase.

Gene ID: 139818

NCBI Accession: NP_653259

UniProt: Q5JSL3