WDR11 antibody (AA 1174-1224)

Catalog No. ABIN7452157

Product Details anti-WDR11 Antibody

Target: WDR11 (WD Repeat Domain 11 (WDR11))

Binding Specificity: AA 1174-1224

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR11 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-WDR11 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1174 and 1224

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for WDR11

Target: WDR11 (WD Repeat Domain 11 (WDR11))

Alternative Name: WDR11 (WDR11 Products)

Synonyms: Brwd2 antibody, WDR11 antibody, PHIP antibody, BRWD2 antibody, DR11 antibody, HH14 antibody, WDR15 antibody, 2900055P10Rik antibody, AW489876 antibody, mKIAA1351 antibody, WD repeat domain 11 antibody, Wdr11 antibody, WDR11 antibody

Background: Background: WDR11 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The WDR11 gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10,19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.[taken from NCBI Entrez Gene (GeneID: 55717)].

Gene ID: 55717

NCBI Accession: NP_060587

UniProt: Q9BZH6