TOM1 antibody (AA 450-492)

Catalog No. ABIN7452105

Product Details anti-TOM1 Antibody

Target: TOM1 (Target of Myb 1 (TOM1))

Binding Specificity: AA 450-492

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-TOM1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 450 and 492

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TOM1

Target: TOM1 (Target of Myb 1 (TOM1))

Alternative Name: TOM1 (TOM1 Products)

Synonyms: TOM-1B antibody, tom-1A antibody, target of myb1 membrane trafficking protein antibody, target of myb1 trafficking protein antibody, TOM1 antibody, Tom1 antibody

Background: Background: TOM1 (target of myb1) was originally identified as a gene activated by the expression of oncogenic Myb1. TOM1 has been shown to form a complex with tollip (toll-interacting protein) and to bind ubiquitin chains. It has also been shown to bind to clathrin heavy chain and is proposed to function to link polyubiquitinated proteins to clathrin and regulate endosomal trafficking of ubiquitinated proteins. Recent evidence shows that TOM1 bridges endofin to clathrin and is critical for the endosomal targeting of clathrin by endofin.

Gene ID: 10043

NCBI Accession: NP_005479

UniProt: O60784