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PDE8B antibody (AA 835-885)

PDE8B Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7451947
  • Target See all PDE8B Antibodies
    PDE8B (phosphodiesterase 8B (PDE8B))
    Binding Specificity
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 835-885
    Reactivity
    • 14
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    This PDE8B antibody is un-conjugated
    Application
    • 12
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Purpose
    Rabbit anti-PDE8B Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogen
    between AA 835 and 885
    Isotype
    IgG
    Top Product
    Discover our top product PDE8B Primary Antibody
  • Application Notes

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Expiry Date
    12 months
  • Target
    PDE8B (phosphodiesterase 8B (PDE8B))
    Alternative Name
    PDE8B (PDE8B Products)
    Synonyms
    PDE8B antibody, ADSD antibody, PPNAD3 antibody, B230331L10Rik antibody, C030047E14Rik antibody, RNPDE8B antibody, phosphodiesterase 8B antibody, high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B antibody, PDE8B antibody, LOC100468338 antibody, pde8b antibody, Pde8b antibody
    Background
    Background: Phosphodiesterase 8B is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. PDE8B, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in the PDE8B gene are a cause of autosomal dominant striatal degeneration (ADSD) [taken from NCBI Entrez Gene (Gene ID: 8622)].
    Gene ID
    8622
    NCBI Accession
    NP_003710
    UniProt
    O95263
    Pathways
    Negative Regulation of Hormone Secretion, cAMP Metabolic Process
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