ERC1 antibody (AA 1000-1050)

Catalog No. ABIN7451773

Product Details anti-ERC1 Antibody

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Binding Specificity: AA 1000-1050

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-ERC1 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1000 and 1050

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ERC1

Target: ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1 (ERC1))

Alternative Name: ERC1 (ERC1 Products)

Synonyms: Cast2 antibody, ELKS antibody, RAB6IP2 antibody, 4930404L01Rik antibody, 5033405M01Rik antibody, 9630025C19Rik antibody, B430107L16Rik antibody, RAB6IP2A antibody, RAB6IP2B antibody, Rab6ip2 antibody, mKIAA1081 antibody, CAST antibody, ERC antibody, ERC1b antibody, Elks antibody, ELKS/RAB6-interacting/CAST family member 1 antibody, ELKS/Rab6-interacting/CAST family member 1 antibody, ERC1 antibody, erc1 antibody, LOC100540472 antibody, Erc1 antibody

Background: Background: ERC1 (ELKS/RAB6-interacting/CAST family member 1) is a regulatory subunit of the IkappaB kinase (IKK) complex. ERC1 probably recruits IkappaBalpha/NFKBIA to the IKK complex. ERC1 may be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release, and may also be involved in vesicle trafficking at the CAZ. ERC1 is also likely involved in Rab-6 regulated endosomes-to- Golgi transport [taken from the Universal Protein Resource (UniProt) Q8IUD2].

Gene ID: 23085

NCBI Accession: NP_829884

UniProt: Q8IUD2

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection