CYFIP1 antibody (AA 1203-1253)

Catalog No. ABIN7451579

Product Details anti-CYFIP1 Antibody

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Binding Specificity: AA 1203-1253

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYFIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-CYFIP1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1203 and 1253

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 5 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CYFIP1

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Alternative Name: CYFIP1 (CYFIP1 Products)

Synonyms: TUBGCP5 antibody, P140SRA-1 antibody, SHYC antibody, SRA1 antibody, E030028J09Rik antibody, P140sra1 antibody, Shyc antibody, Sra-1 antibody, Sra1 antibody, l(7)1Rl antibody, l71Rl antibody, l7Rl1 antibody, mKIAA0068 antibody, pl-1 antibody, CY antibody, CYFIP antibody, fb15a06 antibody, wu:fb15a06 antibody, cytoplasmic FMR1 interacting protein 1 antibody, CYFIP1 antibody, cyfip1 antibody, Cyfip1 antibody

Background: Background: Cytoplasmic FMR1-interacting protein 1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA. CYFIP1 is involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. CYFIP1 may act as an invasion suppressor in cancers [taken from the Universal Protein Resource (UniProt) Q7L576].

Gene ID: 23191

NCBI Accession: NP_055423

UniProt: Q7L576