SH3PXD2B antibody (AA 300-350)

Catalog No. ABIN7451528

Product Details anti-SH3PXD2B Antibody

Target: SH3PXD2B (SH3 and PX Domains 2B (SH3PXD2B))

Binding Specificity: AA 300-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3PXD2B antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-TKS4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 300 and 350

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SH3PXD2B

Target: SH3PXD2B (SH3 and PX Domains 2B (SH3PXD2B))

Alternative Name: TKS4 (SH3PXD2B Products)

Background: Background: TKS4 (tyrosine kinase substrate with four SH4 domains), also known as SH3 and PX domain-containing protein 2B (SH3PXD2B), is an adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. TKS4 binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. TKS4 plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation [taken from the Universal Protein Resource (UniProt) A1X283].

Gene ID: 285590

NCBI Accession: NP_001017995

UniProt: A1X283

Pathways: Positive Regulation of fat Cell Differentiation