DOCK11 antibody (AA 400-450)

Catalog No. ABIN7451432

Product Details anti-DOCK11 Antibody

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Binding Specificity: AA 400-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK11 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-DOCK11 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DOCK11

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Alternative Name: DOCK11 (DOCK11 Products)

Synonyms: ACG antibody, ZIZ2 antibody, bB128O4.1 antibody, 5033414A21Rik antibody, 8030476J24 antibody, Zizimin2 antibody, sph238 antibody, dedicator of cytokinesis 11 antibody, DOCK11 antibody, Dock11 antibody

Background: Background: DOCK11 (dedicator of cytokinesis 11) is also known as zizimin-2. It is a DOCK180-related guanine nucleotide exchange factor (GEF) for the small GTPase, Cdc42. As a GEF, DOCK11 functions to catalyze the dissociation of GDP from the GTPase. Dissociation of GDP allows an exchange for GTP and subsequent downstream signaling by the GTPase.

Gene ID: 139818

NCBI Accession: NP_653259

UniProt: Q5JSL3