TTLL5 antibody (AA 825-875)

Catalog No. ABIN7451352

Product Details anti-TTLL5 Antibody

Target: TTLL5 (Tubulin tyrosine Ligase-Like Family, Member 5 (TTLL5))

Binding Specificity: AA 825-875

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTLL5 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-STAMP Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 825 and 875

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-STAMP antibody ABIN7449831.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TTLL5

Target: TTLL5 (Tubulin tyrosine Ligase-Like Family, Member 5 (TTLL5))

Alternative Name: STAMP (TTLL5 Products)

Synonyms: TTLL5 antibody, KIAA0998 antibody, STAMP antibody, 1700048H13Rik antibody, 2310009M18Rik antibody, 4930556H18Rik antibody, AI428864 antibody, D630041K24Rik antibody, R75373 antibody, Stamp antibody, mKIAA0998 antibody, tubulin tyrosine ligase like 5 antibody, tubulin tyrosine ligase-like family, member 5 antibody, TTLL5 antibody, Ttll5 antibody

Background: Background: SRC1 and TIF2 associated binding protein (STAMP) is a polyglutamylase which preferentially modifies alpha-tubulin. STAMP is involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). It is required for CCSAP localization to both spindle and cilia microtubules. STAMP increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction [taken from the Universal Protein Resource (UniProt) Q6EMB2].

Gene ID: 23093

NCBI Accession: NP_055887

UniProt: Q6EMB2