IQCB1 antibody (AA 548-598)

Catalog No. ABIN7451182

Product Details anti-IQCB1 Antibody

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Binding Specificity: AA 548-598

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCB1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-IQCB1 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 548 and 598

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451182 has not performed satisfactorily when used for WB of IQCB1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of IQCB1.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Alternative Name: IQCB1 (IQCB1 Products)

Synonyms: piq antibody, nphp5 antibody, slsn5 antibody, MGC81507 antibody, IQCB1 antibody, zgc:101792 antibody, MGC146213 antibody, 6820449I09Rik antibody, AV128382 antibody, NPHP5 antibody, PIQ antibody, SLSN5 antibody, IQ motif containing B1 antibody, IQ motif containing B1 L homeolog antibody, IQ calmodulin-binding motif containing 1 antibody, Iqcb1 antibody, iqcb1.L antibody, IQCB1 antibody, iqcb1 antibody

Background: Background: IQ calmodulin-binding motif-containing protein 1 (IQCB1) is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. IQCB1 has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. IQCB1 is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5 [taken from NCBI Entrez Gene (Gene ID: 9657)].

Gene ID: 9657

UniProt: Q15051