MTMR6 antibody (AA 571-621)

Catalog No. ABIN7451181

Product Details anti-MTMR6 Antibody

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Binding Specificity: AA 571-621

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR6 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-MTMR6 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 571 and 621

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451181 has not performed satisfactorily when used for WB of MTMR6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MTMR6.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MTMR6

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Alternative Name: MTMR6 (MTMR6 Products)

Background: Background: Myotubularin-related protein 6 (MTMR6) is a phosphatase that acts on lipids with a phosphoinositol headgroup. MTMR6 acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells [taken from the Universal Protein Resource (UniProt) Q9Y217].

Gene ID: 9107

UniProt: Q9Y217

Pathways: Inositol Metabolic Process