MYO5B antibody (AA 50-100)

Catalog No. ABIN7451161

Product Details anti-MYO5B Antibody

Target: MYO5B (Myosin VB (MYO5B))

Binding Specificity: AA 50-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYO5B antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-MYO5B Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451161 has not performed satisfactorily when used for WB of MYO5B in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MYO5B.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MYO5B

Target: MYO5B (Myosin VB (MYO5B))

Alternative Name: MYO5B (MYO5B Products)

Synonyms: AI661750 antibody, mKIAA1119 antibody, Myr6 antibody, myosin VB antibody, myosin Vb antibody, MYO5B antibody, Myo5b antibody

Background: Background: Myosin 5B may be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. MYO5B is required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Also, together with RAB11A, MYO5B participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A it participates in epithelial cell polarization. Together with RAB25 MYO5B regulates transcytosis [taken from the Universal Protein Resource (UniProt) Q9ULV0].

Gene ID: 4645

UniProt: Q9ULV0