PAPD5 antibody (AA 500-550)

Catalog No. ABIN7451119

Product Details anti-PAPD5 Antibody

Target: PAPD5 (PAP Associated Domain Containing 5 (PAPD5))

Binding Specificity: AA 500-550

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPD5 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-PAPD5/TRF4-2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 500 and 550

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451119 has not performed satisfactorily when used for WB of PAPD5/TRF4-2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PAPD5/TRF4-2.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAPD5

Target: PAPD5 (PAP Associated Domain Containing 5 (PAPD5))

Alternative Name: PAPD5/TRF4-2 (PAPD5 Products)

Synonyms: TRF4-2 antibody, LOC568678 antibody, 5730445M16Rik antibody, 5830428A09 antibody, poly(A) RNA polymerase D5, non-canonical antibody, PAP associated domain containing 5 antibody, PAP associated domain containing 5 L homeolog antibody, PAPD5 antibody, Papd5 antibody, papd5 antibody, CC1G_07969 antibody, papd5.L antibody

Background: Background: Non-canonical poly(A) RNA polymerase PAPD5, also called terminal uridylyltransferase 3 (TUTase 3), is encoded for by the gene PAPD5. TUTase 3 is the catalytic subunit of a TRAMP-like complex which has poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. PAPD5 plays a role in replication-dependent histone mRNA degradation and may play a role in sister chromatid cohesion [taken from UniProtKB (Entry: Q8NDF8)].

Gene ID: 64282

UniProt: Q8NDF8