RC3H2 antibody (AA 1100-1150)

Catalog No. ABIN7451115

Product Details anti-RC3H2 Antibody

Target: RC3H2 (Membrane Associated DNA Binding Protein (RC3H2))

Binding Specificity: AA 1100-1150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RC3H2 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-RC3H2/MNAB Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1100 and 1150

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451115 has not performed satisfactorily when used for WB of RC3H2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of RC3H2.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RC3H2

Target: RC3H2 (Membrane Associated DNA Binding Protein (RC3H2))

Alternative Name: RC3H2/MNAB (RC3H2 Products)

Synonyms: Mnab antibody, MNAB antibody, RNF164 antibody, 2900024N03Rik antibody, 9430019J22Rik antibody, D930043C02Rik antibody, Rnf164 antibody, ring finger and CCCH-type domains 2 antibody, ring finger and CCCH-type zinc finger domains 2 antibody, Rc3h2 antibody, RC3H2 antibody

Background: Background: Roquin-2 is encoded by the gene RC3H2, also known as MNAB. Roquin-2 is a post-transcriptional repressor of mRNAs containing a conserved stem loop motif called the constitutive decay element (CDE). Binding to the CDE promotes mRNA deadenylation and degradation [taken from UniProtKB (Entry: Q9HBD1)].

Gene ID: 54542

UniProt: Q9HBD1