Ataxin 1-Like antibody (AA 250-300)

Catalog No. ABIN7451110

Product Details anti-Ataxin 1-Like Antibody

Target: Ataxin 1-Like (ATXN1L)

Binding Specificity: AA 250-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 1-Like antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-ATXN1L Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 250 and 300

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451110 has not performed satisfactorily when used for WB of ATXN1L in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of ATXN1L.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Ataxin 1-Like

Target: Ataxin 1-Like (ATXN1L)

Alternative Name: ATXN1L (ATXN1L Products)

Background: Background: Ataxin-1-like, encoded by the gene ATXN1L, is a chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. ATXN1L can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) [taken from UniProtKB (Entry: P0C7T5)].

Gene ID: 342371

UniProt: P0C7T5