Serotonin Receptor 6 antibody (AA 1-50)

Catalog No. ABIN7451067

Product Details anti-Serotonin Receptor 6 Antibody

Target: Serotonin Receptor 6 (HTR6)

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 6 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-5-HT6 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451067 has not performed satisfactorily when used for WB of 5-HT6 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of 5-HT6 .

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Serotonin Receptor 6

Target: Serotonin Receptor 6 (HTR6)

Alternative Name: 5-HT6 (HTR6 Products)

Synonyms: 5-HT6 antibody, 5-HT6R antibody, 5-hydroxytryptamine (serotonin) receptor 6 antibody, 5-hydroxytryptamine receptor 6 antibody, Htr6 antibody, HTR6 antibody

Background: Background: 5-HT6 is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs [taken from the Universal Protein Resource (UniProt) P50406].

Gene ID: 3362

NCBI Accession: NP_000862

UniProt: P50406

Pathways: JAK-STAT Signaling