SUCLA2 antibody (AA 413-463)

Catalog No. ABIN7451030

Product Details anti-SUCLA2 Antibody

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Binding Specificity: AA 413-463

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUCLA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-SUCLA2 Antibody, Affinity Purified

Predicted Reactivity: Bovine,Pig,Golden hamster

Purification: Affinity Purified

Immunogen: Between AA 413 and 463

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SUCLA2

Target: SUCLA2 (Succinate-CoA Ligase, ADP-Forming, beta Subunit (SUCLA2))

Alternative Name: SUCLA2 (SUCLA2 Products)

Synonyms: 4930547K18Rik antibody, A-BETA antibody, MTDPS5 antibody, SCS-betaA antibody, SCS antibody, succinate-Coenzyme A ligase, ADP-forming, beta subunit antibody, succinate-CoA ligase ADP-forming beta subunit antibody, Sucla2 antibody, SUCLA2 antibody

Background: Background: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. SUCLA2 is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA [taken from NCBI Entrez Gene (Gene ID: 8803)].

Gene ID: 8803

UniProt: Q9P2R7