VAC14 antibody (AA 732-782)
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- Target See all VAC14 Antibodies
- VAC14 (Vac14 Homolog (VAC14))
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Binding Specificity
- AA 732-782
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This VAC14 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Purpose
- Rabbit anti-VAC14 Antibody, Affinity Purified
- Predicted Reactivity
- Rat,Bovine
- Purification
- Affinity Purified
- Immunogen
- Between AA 732 and 782
- Isotype
- IgG
- Top Product
- Discover our top product VAC14 Primary Antibody
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- Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- VAC14 (Vac14 Homolog (VAC14))
- Alternative Name
- VAC14 (VAC14 Products)
- Synonyms
- ArPIKfyve antibody, TAX1BP2 antibody, TRX antibody, AA959718 antibody, BC032215 antibody, D8Wsu151e antibody, Tax1bp2 antibody, Trx antibody, ingls antibody, Vac14 homolog L homeolog antibody, Vac14, PIKFYVE complex component antibody, Vac14 homolog (S. cerevisiae) antibody, vac14.L antibody, VAC14 antibody, Vac14 antibody
- Background
- Background: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) [taken from NCBI Entrez Gene (Gene ID: 55697)].
- Gene ID
- 55697
- UniProt
- Q08AM6
- Pathways
- Inositol Metabolic Process
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