Strumpellin antibody (AA 1109-1159)

Catalog No. ABIN7450762

Product Details anti-Strumpellin Antibody

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Binding Specificity: AA 1109-1159

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Strumpellin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-SPG8/Strumpellin Antibody, Affinity Purified

Predicted Reactivity: Zebrafish,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 1109 and 1159

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Strumpellin

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Alternative Name: SPG8/Strumpellin (WASHC5 Products)

Synonyms: SPG8 antibody, AL022848 antibody, C76463 antibody, Kiaa0196 antibody, mKIAA0196 antibody, strumpellin antibody, WASH complex subunit 5 antibody, WASHC5 antibody, washc5 antibody, Washc5 antibody

Background: Background: SPG8/Strumpellin acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). SPG8/Strumpellin may be involved in axonal outgrowth [taken from the Universal Protein Resource (UniProt) Q12768].

Gene ID: 9897

UniProt: Q12768