SOS2 antibody (AA 1282-1332)

Catalog No. ABIN7450757

Product Details anti-SOS2 Antibody

Target: SOS2 (Son of Sevenless Homolog 2 (SOS2))

Binding Specificity: AA 1282-1332

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-SOS2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1282 and 1332

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SOS2

Target: SOS2 (Son of Sevenless Homolog 2 (SOS2))

Alternative Name: SOS2 (SOS2 Products)

Synonyms: Sos1 antibody, SOS-2 antibody, mSOS-2 antibody, SOS Ras/Rho guanine nucleotide exchange factor 2 antibody, son of sevenless homolog 2 (Drosophila) antibody, Sos2 antibody, SOS2 antibody

Background: Background: SOS2 (son of sevenless homolog 2) is a human paralog of the Drosophila SOS gene. Drosophila SOS was originally identified as a gene that functioned downstream of the sevenless gene in the Ras/MAP kinase signaling pathway. SOS and its paralogs, SOS1 and SOS2, function as guanine nucleotide exchange factors that act on Ras-GTPases to cause release of GDP in exchange for GTP. Although targeted disruption of SOS1 results in embryonic lethality, disruption of SOS2 does not have any effects on mouse development, growth, or fertility.

Gene ID: 6655

NCBI Accession: NP_008870

UniProt: Q07890

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, Hepatitis C, BCR Signaling