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SH3BP2 antibody (AA 150-200)

SH3BP2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7450726
  • Target See all SH3BP2 Antibodies
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-200
    Reactivity
    • 39
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 35
    • 4
    • 1
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3BP2 antibody is un-conjugated
    Application
    • 27
    • 20
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Purpose
    Rabbit anti-SH3BP2 Antibody, Affinity Purified
    Purification
    Affinity Purified
    Immunogen
    between AA 150 and 200
    Isotype
    IgG
    Top Product
    Discover our top product SH3BP2 Primary Antibody
  • Application Notes

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    1000 μg/mL
    Buffer
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Expiry Date
    12 months
  • Target
    SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
    Alternative Name
    SH3BP2 (SH3BP2 Products)
    Synonyms
    SH3BP2 antibody, 3BP-2 antibody, 3BP2 antibody, CRBM antibody, CRPM antibody, SH3 domain binding protein 2 antibody, SH3-domain binding protein 2 antibody, SH3BP2 antibody, Sh3bp2 antibody
    Background
    Background: SH3 domain-binding protein 2 (SH3BP2) N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism, an autosomal dominant inherited syndrome characterized by excessive bone degradation of the upper and lower jaws followed by development of fibrous tissue masses and characteristic facial swelling [taken from NCBI Entrez Gene (Gene ID: 6452)].
    Gene ID
    6452
    NCBI Accession
    NP_001116153
    UniProt
    P78314
    Pathways
    TCR Signaling
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