POLR3E antibody (AA 475-525)

Catalog No. ABIN7450584

Product Details anti-POLR3E Antibody

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Binding Specificity: AA 475-525

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR3E antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-POLR3E Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 475 and 525

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for POLR3E

Target: POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))

Alternative Name: POLR3E (POLR3E Products)

Synonyms: RPC5 antibody, SIN antibody, Sin antibody, MGC78924 antibody, RGD1308086 antibody, wu:fb12d10 antibody, wu:fs42e03 antibody, zgc:55592 antibody, RNA polymerase III subunit E antibody, polymerase (RNA) III (DNA directed) polypeptide E antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, POLR3E antibody, Polr3e antibody, polr3e.L antibody, polr3e antibody, LOC608689 antibody

Background: Background: POLR3E (RNA polymerase III polypeptide E 80 kDa) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3E is a specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. POLR3E plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses [taken from the Universal Protein Resource (UniProt) Q9NVU0].

Gene ID: 55718

NCBI Accession: NP_060589

UniProt: Q9NVU0