PATL1 antibody (AA 425-475)

Catalog No. ABIN7450546

Product Details anti-PATL1 Antibody

Target: PATL1 (Protein Associated with Topoisomerase II Homolog 1 (PATL1))

Binding Specificity: AA 425-475

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PATL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-Pat1b Antibody, Affinity Purified

Predicted Reactivity: Mouse,Orangutan

Purification: Affinity Purified

Immunogen: between AA 425 and 475

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PATL1

Target: PATL1 (Protein Associated with Topoisomerase II Homolog 1 (PATL1))

Alternative Name: Pat1b (PATL1 Products)

Synonyms: Pat1b antibody, xPat1b antibody, hPat1b antibody, AV312086 antibody, D430024J04 antibody, RGD1305514 antibody, fa11d04 antibody, wu:fa11d04 antibody, zgc:158239 antibody, PAT1 homolog 1, processing body mRNA decay factor antibody, protein associated with topoisomerase II homolog 1 L homeolog antibody, protein associated with topoisomerase II homolog 1 (yeast) antibody, PATL1 antibody, patl1.L antibody, Patl1 antibody, patl1 antibody

Background: Background: Pat1 homolog b (Pat1b) is an RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Pat1b acts as a scaffold protein that connects deadenylation and decapping machinery. Pat1b is required for cytoplasmic mRNA processing body (P-body) assembly, and in cases of infection, it is required for translation and replication of hepatitis C virus (HCV) [taken from the Universal Protein Resource (UniProt) Q86TB9].

Gene ID: 219988

NCBI Accession: NP_689929

UniProt: Q86TB9

Pathways: Ribonucleoprotein Complex Subunit Organization