N-Glycanase 1 antibody (AA 250-300)

Catalog No. ABIN7450495

Product Details anti-N-Glycanase 1 Antibody

Target: N-Glycanase 1 (NGLY1)

Binding Specificity: AA 250-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This N-Glycanase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-NGLY1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 250 and 300

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for N-Glycanase 1

Target: N-Glycanase 1 (NGLY1)

Alternative Name: NGLY1 (NGLY1 Products)

Background: Background: NGLY1 is an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. NGLY1 may play a role in the proteasome-mediated degradation of misfolded glycoproteins [taken from NCBI Entrez Gene (Gene ID: 55768)].

Gene ID: 55768

UniProt: Q96IV0

Pathways: Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome