PMPCB antibody (AA 571-621)

Catalog No. ABIN7450459

Product Details anti-PMPCB Antibody

Target: PMPCB (Peptidase (Mitochondrial Processing) beta (PMPCB))

Binding Specificity: AA 571-621

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMPCB antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-MPP11 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 571 and 621

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PMPCB

Target: PMPCB (Peptidase (Mitochondrial Processing) beta (PMPCB))

Alternative Name: MPP11 (PMPCB Products)

Synonyms: Beta-MPP antibody, MPP11 antibody, MPPB antibody, MPPP52 antibody, P-52 antibody, Mppb antibody, 3110004O18Rik antibody, MGC78954 antibody, PMPCB antibody, zgc:110738 antibody, Pmpcb antibody, peptidase, mitochondrial processing beta subunit antibody, peptidase (mitochondrial processing) beta antibody, peptidase (mitochondrial processing) beta L homeolog antibody, PMPCB antibody, Pmpcb antibody, pmpcb.L antibody, pmpcb antibody

Background: Background: M-phase phosphoprotein 11 is a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. MPP11 is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. MPP11 was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Additionally, chromosomal aberrations involving the DNAJC2 gene are associated with primary head and neck squamous cell tumors [taken from NCBI Entrez Gene (Gene ID: 27000)].

Gene ID: 27000

NCBI Accession: NP_055192

UniProt: Q99543

Pathways: SARS-CoV-2 Protein Interactome