GCC2 antibody (AA 1-50)

Catalog No. ABIN7450275

Product Details anti-GCC2 Antibody

Target: GCC2 (GRIP and Coiled-Coil Domain Containing 2 (GCC2))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-GCC185 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for GCC2

Target: GCC2 (GRIP and Coiled-Coil Domain Containing 2 (GCC2))

Alternative Name: GCC185 (GCC2 Products)

Synonyms: GCC185 antibody, RANBP2L4 antibody, REN53 antibody, 0610043A03Rik antibody, 2210420P05Rik antibody, 2600014C01Rik antibody, AW112121 antibody, mKIAA0336 antibody, Lims1 antibody, GRIP and coiled-coil domain containing 2 antibody, GCC2 antibody, gcc2 antibody, Gcc2 antibody

Background: Background: 185 kDa Golgi coiled-coil protein (GCC85) is a Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector, GCC85 is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. Golgin may also play a role in transport between the recycling endosomes and the Golgi. It is required for maintenance of the Golgi structure, and it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2. RanBP2L4, renal carcinoma antigen NY-REN-53, and KIAA0336 [taken from the Universal Protein Resource (UniProt) Q81WJ2].

Gene ID: 9648

NCBI Accession: NP_852118

UniProt: Q8IWJ2

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome