RFWD2 antibody (AA 1-50)
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- Target See all RFWD2 Antibodies
- RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))
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Binding Specificity
- AA 1-50
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RFWD2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Purpose
- Rabbit anti-COP1/RFWD2 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- Between AA 1 and 50
- Isotype
- IgG
- Top Product
- Discover our top product RFWD2 Primary Antibody
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anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) (AA 632-731) antibody
RFWD2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1E4 unconjugated
anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) (Internal Region) antibodyRFWD2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) (AA 37-65), (N-Term) antibodyRFWD2 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB19572 unconjugated
anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) (AA 672-701), (C-Term) antibodyRFWD2 Reactivity: Human WB Host: Rabbit Polyclonal RB41831 unconjugated
anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) antibodyRFWD2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) (Tyr762) antibodyRFWD2 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) (AA 301-350) antibodyRFWD2 Reactivity: Human, Mouse, Rabbit, Cow, Horse, Dog, Guinea Pig, Pig, Bat, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2) (AA 582-731) antibodyRFWD2 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- RFWD2 (Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))
- Alternative Name
- COP1/RFWD2 (RFWD2 Products)
- Synonyms
- COP1 antibody, RNF200 antibody, AI316802 antibody, C80879 antibody, Cop1 antibody, RGD1304773 antibody, RFWD2 antibody, cop1 antibody, rnf200 antibody, zgc:163067 antibody, ring finger and WD repeat domain 2 antibody, ring finger and WD repeat domain 2, E3 ubiquitin protein ligase antibody, ring finger and WD repeat domain 2, E3 ubiquitin protein ligase L homeolog antibody, RFWD2 antibody, Rfwd2 antibody, rfwd2 antibody, rfwd2.L antibody
- Background
- Background: Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities.
- Gene ID
- 64326
- NCBI Accession
- NP_071902
- UniProt
- Q8NHY2
- Pathways
- Photoperiodism
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