MAML1 antibody (AA 75-125)
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- Target See all MAML1 Antibodies
- MAML1 (Mastermind-Like 1 (MAML1))
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Binding Specificity
- AA 75-125
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAML1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Purpose
- Rabbit anti-MAML1 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- between AA 75 and 125
- Isotype
- IgG
- Top Product
- Discover our top product MAML1 Primary Antibody
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- Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- MAML1 (Mastermind-Like 1 (MAML1))
- Alternative Name
- MAML1 (MAML1 Products)
- Synonyms
- mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
- Background
- Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
- Gene ID
- 9794
- NCBI Accession
- NP_055572
- UniProt
- Q92585
- Pathways
- Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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