SLBP antibody (AA 220-270)

Catalog No. ABIN7449822

Product Details anti-SLBP Antibody

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Binding Specificity: AA 220-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLBP antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-SLBP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 220 and 270

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SLBP

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Alternative Name: SLBP (SLBP Products)

Background: Background: Stem-loop-binding protein (SLBP) is an RNA-binding protein involved in the histone pre-mRNA processing. SLBP binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). SLBP plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. It stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. It is also involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. SLBP binds to the 5' side of the stem-loop structure of histone pre-mRNAs [taken from the Universal Protein Resource (UniProt) Q14493].

Gene ID: 7884

NCBI Accession: NP_006518

UniProt: Q14493