DDX10 antibody (C-Term)

Catalog No. ABIN7449582

Product Details anti-DDX10 Antibody

Target: DDX10 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10 (DDX10))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX10 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-DDX10 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 825 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 1 - 4 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DDX10

Target: DDX10 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10 (DDX10))

Alternative Name: DDX10 (DDX10 Products)

Synonyms: DDX10 antibody, ddx10 antibody, MGC144959 antibody, Ddx10 antibody, HRH-J8 antibody, 4632415A01Rik antibody, AI646054 antibody, DEAD-box helicase 10 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 antibody, DEAD-box helicase 10 L homeolog antibody, Ddx10 antibody, DDX10 antibody, ddx10 antibody, LOC656831 antibody, ddx10.L antibody

Background: Background: DDX10 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX10 may play a particular role in ribosome assembly. DDX10 has been observed to be involved in a chromosomal translocation and fused with the nucleoporin gene, NUP98, in myeloid malignancies.

Gene ID: 1662

NCBI Accession: NP_004389

UniProt: Q13206

Pathways: SARS-CoV-2 Protein Interactome