MCM10 antibody (AA 600-650)

Catalog No. ABIN7449575

Product Details anti-MCM10 Antibody

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Binding Specificity: AA 600-650

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM10 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-MCM10 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

IP: 1 - 4 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MCM10

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Alternative Name: MCM10 (MCM10 Products)

Background: Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM10 (Mini-Chromosome Maintenance 10) is not a member of the canonical six that form the MCM complex. MCM10 appears to interact with all members of the MCM complex and functions as a factor that recruits the MCM complex to the pre-replication complex (pre-RC) on DNA.

Gene ID: 55388

NCBI Accession: NP_060988

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication