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Recombinant GZMB antibody (AA 19-247)

GZMB Reactivity: Human WB, IHC, ICC, IF (p), mIF Host: Rabbit Monoclonal BLR022E unconjugated Recombinant Antibody

Catalog No. ABIN7449554

Datasheet as PDF

Target See all GZMB Antibodies

GZMB (Granzyme B (GZMB))

Antibody Type

Recombinant Antibody
Binding Specificity
18

16

13

10

10

4

2

2

2

2

2

2

2

1

1

1

1

1

1
AA 19-247
Reactivity
125

48

24

10

4

2

1

1
Human
Host
82

45

2
Rabbit
Compatible Secondaries
Clonality
81

48
Monoclonal
Conjugate
75

12

7

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This GZMB antibody is un-conjugated
Application
69

41

39

36

18

17

16

13

13

9

8

6

6

5

2

2

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Multiplex Immunofluorescence (mIF)

Purpose

Rabbit anti-Granzyme B Recombinant Monoclonal Antibody [BLR022E]

Immunogen

residues 19-247 (mature protein)

Clone

BLR022E

Isotype

IgG

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anti-Granzyme B (GZMB) (AA 21-247) antibody
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anti-Granzyme B (GZMB) (AA 73-187) antibody
GZMB Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal GZMB-3014 unconjugated

anti-Granzyme B (GZMB) (AA 21-130) antibody
GZMB Reactivity: Human, Mouse WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Granzyme B (GZMB) antibody
GZMB Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Granzyme B (GZMB) antibody
GZMB Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CLB-GB11 unconjugated

anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibody
GZMB Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19353 unconjugated

anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 2G12G7 unconjugated

anti-Granzyme B (GZMB) (AA 1-247) antibody
GZMB Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Granzyme B (GZMB) (AA 73-187) antibody
GZMB Reactivity: Human IHC, StM Host: Mouse Monoclonal GZMB-3056 unconjugated

anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 4E4 unconjugated

Application Notes

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 17:40:00

Restrictions

For Research Use only
Concentration

50 μg/mL

Buffer

Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Expiry Date

12 months
Target

GZMB (Granzyme B (GZMB))

Alternative Name

Granzyme B (GZMB Products)

Synonyms

CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody

Background

Background: Granzyme B is a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing [taken from NCBI Entrez Gene (Gene ID: 3002)]

Gene ID

3002

NCBI Accession

NP_004122

UniProt

P10144

Pathways

Apoptosis, Caspase Cascade in Apoptosis