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CD45RO antibody

CD45RO Reactivity: Human WB, IHC, IF (p), ICC, mIF Host: Mouse Monoclonal UCHL-1 unconjugated

Catalog No. ABIN7449553

Datasheet as PDF

Target See all CD45RO products

CD45RO
Reactivity
66

12

12

11

11
Human
Host
54

12
Mouse
Compatible Secondaries
Clonality
54

12
Monoclonal
Conjugate
10

4

4

3

3

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD45RO antibody is un-conjugated
Application
52

27

21

13

10

9

9

8

4

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)

Purpose

Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]

Immunogen

Cultured T-cells from an IL-2-dependent T-cell line (CA1)

Clone

UCHL-1

Isotype

IgG
anti-CD45RO (CD45RO) antibody
CD45RO Reactivity: Human, Mouse, Rat WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated

anti-CD45RO (CD45RO) antibody
GMP Grade CD45RO Reactivity: Human FACS, IHC, IP Host: Mouse Monoclonal UCHL1 unconjugated

anti-CD45RO (CD45RO) antibody (FITC)
GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 FITC

anti-CD45RO (CD45RO) antibody (PE)
GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 PE

anti-CD45RO (CD45RO) antibody (APC)
GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 APC

anti-CD45RO (CD45RO) antibody (mFluor™450)
GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 mFluor™450

anti-CD45RO (CD45RO) antibody (PE-CF®594)
GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 PE-CF®594

anti-CD45RO (CD45RO) antibody
CD45RO Reactivity: Human, Chimpanzee, Marmoset FACS, IF, IHC (p) Host: Mouse Monoclonal UCHL-1 unconjugated

anti-CD45RO (CD45RO) antibody (FITC)
CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 FITC

anti-CD45RO (CD45RO) antibody (PE)
CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 PE

Application Notes

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 05:10:00

Restrictions

For Research Use only
Concentration

50 μg/mL

Buffer

Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Expiry Date

12 months
Target

CD45RO

Alternative Name

CD45RO (CD45RO Products)

Background

Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].

Gene ID

5788

NCBI Accession

NP_002829

UniProt

P08575