FAM126A antibody (AA 400-450)

Catalog No. ABIN7449095

Product Details anti-FAM126A Antibody

Target: FAM126A (Family with Sequence Similarity 126, Member A (FAM126A))

Binding Specificity: AA 400-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM126A antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-FAM126A Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: Between AA 400 and 450

Isotype: IgG

Application Details

Application Notes: 8 - 15 μL/mg lysate

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FAM126A

Target: FAM126A (Family with Sequence Similarity 126, Member A (FAM126A))

Alternative Name: FAM126A (FAM126A Products)

Synonyms: DRCTNNB1A antibody, HCC antibody, HLD5 antibody, HYCC1 antibody, AB030242 antibody, Drctnnb1a antibody, RGD1562906 antibody, zgc:77228 antibody, fam126a antibody, family with sequence similarity 126 member A antibody, family with sequence similarity 126, member A antibody, family with sequence similarity 126 member A S homeolog antibody, FAM126A antibody, Fam126a antibody, fam126a antibody, fam126a.S antibody

Background: Background: FAM126A is a component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane (PubMed:26571211). The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (PubMed:26571211). FAM126A plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P (PubMed:26571211). Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system (PubMed:26571211, PubMed:16951682). FAM126A may also have a role in the beta-catenin/Lef signaling pathway (Probable) [taken from the Universal Protein Resource (UniProt) Q9BYI3].

Gene ID: 84668

UniProt: Q9BYI3