YTHDF1 antibody (AA 1-50)

Catalog No. ABIN7449074

Product Details anti-YTHDF1 Antibody

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YTHDF1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Purpose: Rabbit anti-YTHDF1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 15-20 μL/mg lysate

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for YTHDF1

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Alternative Name: YTHDF1 (YTHDF1 Products)

Background: Background: YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation.

Gene ID: 54915

UniProt: Q9BYJ9