WRNIP1 antibody (AA 400-450)

Catalog No. ABIN7449035

Product Details anti-WRNIP1 Antibody

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Binding Specificity: AA 400-450

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WRNIP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purpose: Rabbit anti-WRNIP1 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Dog,Horse,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Small-eared galago,Ferret,Chinese hamster,Northern white-cheeked gibbon,Naked mole rat,Crab-eating macaque,White-tufted-ear marmoset,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogen: Between AA 400 and 450

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for WRNIP1

Target: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Alternative Name: WRNIP1 (WRNIP1 Products)

Background: Background: WRNIP1 (Werner helicase interacting protein 1) was identified as a protein that interacts with the N-terminal region of Werner protein (WRN). WRN is a RecQ DNA helicase important to DNA repair and is the causative gene of Werner syndrome (WS), an autosomal recessive disease characterized by premature aging. WRNIP1 has been shown to interact with DNA polymerase delta (pol delta) and play a role in pol delta-mediated DNA synthesis. Additionally, WRNIP1 has been shown to interact with polyubiquitin chains indicating a link between ubiquitination and the DNA repair pathway.

Gene ID: 56897

NCBI Accession: NP_064520

UniProt: Q96S55