Rad6 (N-Term) antibody

Catalog No. ABIN7448752

Product Details

Target: Rad6

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-Rad6 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,D. melanogaster,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Atlantic salmon,Tasmanian devil,Rainbow smelt,Rainbow trout,Nile tilapia,Ferret,Yeast_237561,Killifish,African elephant,Medaka fish,Thirteen-lined ground squirrel,Yeast_284593,Zebra finch,Little brown bat,Teleostei,Small-eared galago,Japanese pufferfish,Naked mole rat,Green anole,Northern white-cheeked gibbon,Sablefish,Red sea bream,Northern pike,West Indian ocean coelacanth,Baker's yeast_559292,Spotted green pufferfish,Three-spined stickleback,Yeast_284811,Yeast_284590

Purification: Affinity Purified

Immunogen: N-terminus

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: Rad6

Background: Background: Rad 6, also known as Ubiquitin conjugating enzyme E2A, is an E2 enzyme of the three step ubiquitination pathway. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ubiquitination provides an important post-translational means to regulate protein abundance and activity. Rad6 has been demonstrated to be important to DNA damage repair. Mutations in Rad6 cause an X-linked mental retardation syndrome.

Gene ID: 7319

NCBI Accession: NP_003327

UniProt: P49459