POLE3 antibody (AA 97-147)

Catalog No. ABIN7448733

Product Details anti-POLE3 Antibody

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Binding Specificity: AA 97-147

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLE3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-PolE3/p17 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Chinese hamster,Crab-eating macaque,Little brown bat,Small-eared galago,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 97 and 147

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for POLE3

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Alternative Name: PolE3/p17 (POLE3 Products)

Background: Background: PolE3/p17 is a subunit of DNA polymerase epsilon that plays a role in DNA replication and repair. PolE3/p17 contains histone-fold motifs which play a role in protein-protein and protein-DNA interactions. PolE3/p17 interacts with CHRAC1 (chromatin assembly complex 1), ACF1, and ISWI/SNF2H proteins to form the CHRAC ISWI chromatin-remodeling complex.

Gene ID: 54107

NCBI Accession: NP_059139

UniProt: Q9NRF9

Pathways: DNA Damage Repair