PALB2 antibody (AA 200-250)

Catalog No. ABIN7448714

Product Details anti-PALB2 Antibody

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Binding Specificity: AA 200-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PALB2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-PALB2 IHC Antibody, affinity purified

Predicted Reactivity: Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 200 and 250

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PALB2

Target: PALB2 (Partner and Localizer of BRCA2 (PALB2))

Alternative Name: PALB2 (PALB2 Products)

Background: Background: PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.

Gene ID: 79728

NCBI Accession: NP_078951

UniProt: Q86YC2

Pathways: DNA Damage Repair