NCOA2 antibody (C-Term)

Catalog No. ABIN7448683

Product Details anti-NCOA2 Antibody

Target: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-NCOA2/SRC2 IHC Antibody, Affinity Purified

Predicted Reactivity: Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 1400 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NCOA2

Target: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Alternative Name: NCOA2/SRC2 (NCOA2 Products)

Background: Background: Nuclear Receptor Coactivator 2 (NCOA2) is a member of the p160 family of nuclear receptor coactivators that also includes steroid receptor coactivator-1 (SRC-1) and p300/CBP-interacting protein (p/CIP). As Coactivators, this group of proteins helps recruit acetyltransferases and methyltransferases such as p300/CBP and CARM1 to facilitate chromatin remodeling and transcription factor recruitment, and to enhance gene expression. NCOA2 has been demonstrated to be important for the control of energy balance between white and brown adipose tissue.

Gene ID: 10499

NCBI Accession: NP_006531

UniProt: Q15596

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling