MKRN1 antibody (C-Term)

Catalog No. ABIN7448670

Product Details anti-MKRN1 Antibody

Target: MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKRN1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-MKRN1 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Ferret,Crab-eating macaque,Small-eared galago,Naked mole rat,Little brown bat,Thirteen-lined ground squirrel,White-tufted-ear marmoset,African elephant,Northern white-cheeked gibbon,Chinese hamster

Purification: Affinity Purified

Immunogen: Between AA 432 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MKRN1

Target: MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))

Alternative Name: MKRN1 (MKRN1 Products)

Background: Background: MKRN1 was identified as a repressor of c-Jun, androgen receptor, and retinoic acid receptor transcriptional activity. MKRN1 is a RING zinc finger protein that has been demonstrated to function as an E3 ubiquitin ligase. The repressive activity of MKRN1 is not dependent on its ubiquitin ligase activity. MKRN1 also appears to function as a transactivator of RNA polymerase II dependent transcription.

Gene ID: 23608

NCBI Accession: NP_038474

UniProt: Q9UHC7

Pathways: Chromatin Binding