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MAML1 antibody (AA 75-125)
MAML1
Reactivity: Human
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAML1 Antibody
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Target
See all MAML1 Antibodies
MAML1
(Mastermind-Like 1 (MAML1))
Binding Specificity
All epitopes for MAML1 antibodies
AA 75-125
Reactivity
All reactivities for MAML1 antibodies
Human
Host
All hosts for MAML1 antibodies
Rabbit
Clonality
All clonalities for MAML1 antibodies
Polyclonal
Conjugate
All conjugates for MAML1 antibodies
This MAML1 antibody is un-conjugated
Application
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Immunohistochemistry (IHC)
Purpose
Rabbit anti-MAML1 IHC Antibody, Affinity Purified
Predicted Reactivity
Chimpanzee
Purification
Affinity Purified
Immunogen
Between AA 75 and 125
Isotype
IgG
Top Product
Discover our top product MAML1 Primary Antibody
Alternatives
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Application Details
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Application Notes
1:100 - 1:500
Restrictions
For Research Use only
Handling
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Concentration
250 μg/mL
Buffer
Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Expiry Date
12 months
Target Details for MAML1
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Target
MAML1
(Mastermind-Like 1 (MAML1))
Alternative Name
MAML1 (MAML1 Products )
Synonyms
mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
Background
Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
Gene ID
9794
NCBI Accession
NP_055572
UniProt
Q92585
Pathways
Notch Signaling , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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