EML4 antibody (AA 150-200)

Catalog No. ABIN7448551

Product Details anti-EML4 Antibody

Target: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Binding Specificity: AA 150-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EML4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Purpose: Rabbit anti-EML4 IHC Antibody, Affinity Purified

Predicted Reactivity: Rabbit,Guinea pig_10141,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Northern white-cheeked gibbon,Thirteen-lined ground squirrel,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 150 and 200

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EML4

Target: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Alternative Name: EML4 (EML4 Products)

Background: Background: Echinoderm microtubule associated protein like 4 (EML4) has been identified as part of a gene fusion with the kinase domain of the anaplastic lymphoma receptor tyrosine kinase (ALK) in non-small cell lung cancer. EML4 associates with in vitro polymerized microtubules. In the cell, phosphorylated EML4 associates with the mitotic spindle and is essential for proliferation and microtubule network formation.

Gene ID: 27436

NCBI Accession: NP_061936

UniProt: Q9HC35